BISMARCK, N.D. (AP) — The North Dakota Department of Health has reported two suspected severe allergic reactions to the Moderna COVID-19 vaccine. The two people had no history of anaphylactic reactions and the incidents were unrelated.

Neither person was hospitalized, and they have both since recovered. The allergic reactions occurred during a 15-minute post-vaccine observation period recommended by the Centers for Disease Control and Prevention.

State health officials say anaphylactic reactions after being vaccinated are rare. For other vaccines, they occur at a rate of one per 1 million doses.